SNCA monoclonal antibody (M01), clone 2E4
产品名称: SNCA monoclonal antibody (M01), clone 2E4
英文名称: SNCA monoclonal antibody (M01), clone 2E4
产品编号: H00006622-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Mouse monoclonal antibody raised against a partial recombinant SNCA.
 
- Immunogen:
 - SNCA (NP_000336, 31 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
 
- Sequence:
 - GKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
 
- Host:
 - Mouse
 
- Reactivity:
 - Human
 
- Isotype:
 - IgG2a kappa
 
- Storage Buffer:
 - In 1x PBS, pH 7.2
 
- Storage Instruction:
 - Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - Antibody Reactive Against Recombinant Protein.

Western Blot detection against Immunogen (37.84 KDa) . 
- MSDS:
 
Download
- Applications
 
- Western Blot (Transfected lysate)
 
- Western Blot analysis of SNCA expression in transfected 293T cell line by SNCA monoclonal antibody (M01), clone 2E4.
Lane 1: SNCA transfected lysate(14.5 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
 
- Western Blot (Recombinant protein)
 - Protocol Download
 
- Immunoprecipitation
 
- Immunoprecipitation of SNCA transfected lysate using anti-SNCA monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SNCA MaxPab rabbit polyclonal antibody.
 - Protocol Download
 
- Sandwich ELISA (Recombinant protein)
 
- Detection limit for recombinant GST tagged SNCA is 0.1 ng/ml as a capture antibody.
 - Protocol Download
 
- Entrez GeneID:
 - 6622
 
- GeneBank Accession#:
 - NM_000345
 
- Protein Accession#:
 - NP_000336
 
- Gene Name:
 - SNCA
 
- Gene Alias:
 - MGC110988,NACP,PARK1,PARK4,PD1
 
- Gene Description:
 - synuclein, alpha (non A4 component of amyloid precursor)
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
 
- Other Designations:
 - OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
 
- Interactome
 
- Gene Pathway
 
- Related Disease
 
- Alcoholism
 - Alzheimer Disease
 - Alzheimer disease
 - Amphetamine-Related Disorders
 - Association Learning
 - Attention
 - Cardiovascular Diseases
 - Chromosome Breakage
 - Cognition Disorders
 - Color Perception
 - Cystic Fibrosis
 - Cystic fibrosis
 - Dementia
 - Diabetes Complications
 - Disease Progression
 - Disease Susceptibility
 - Essential Tremor
 - Essential tremor
 - Genetic Predisposition to Disease
 

