Anti-AIFM1 Monoclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-AIFM1  Monoclonal Antibody

Anti-AIFM1 Monoclonal Antibody

商家询价

产品名称: Anti-AIFM1 Monoclonal Antibody

英文名称: Anti-AIFM1 Monoclonal Antibody

产品编号: K000163M

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-02-07T13:54:15

使用范围: WB IF

北京索莱宝科技有限公司
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Anti-AIFM1 Monoclonal Antibody

品牌:solarbio | 货号:K000163M
 
宿主Mouse
英文名称Anti-AIFM1 Monoclonal Antibody
别名AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8
应用WB IF
稀释比例WB 1:1000. ICC 1:200.
交叉反应Human
蛋白分子量67kDa
Gene ID9131
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG2a
免疫原Purified recombinant human AIFM1 protein fragments expressed in E.coli.
性状液体
Subcellular LocationsCytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region
Swiss ProtO95831
克隆号8H1-B10-A12
克隆类型Monoclonal Antibody
背景资料This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.